General Health

Restylane® Refyne, Defyne, Silk & Lyft – What’s the difference?

Restylane® is a popular, versatile line of cosmetic injectables that includes Restylane – Refyne, Defyne, Silk, and Lyft. They have a lot of options to choose from, so if you are interested in cosmetic injectable treatment you may be wondering: What’s the difference between Restylane Refyne, Defyne, Silk and Lyft?

Facial Aging

Facial aging is characterized by the emergence of fine lines and wrinkles that are usually the result of the loss of volume and elastic support. Volume loss is caused by a decline in vital skin components such as collagen, elastin, and hyaluronic acid. Dermal fillers such as Restylane can revitalize the skin and restore its plump, youthful appearance.

Restylane® for facial rejuvenation

Restylane products are made from hyaluronic acid (HA). HA is a substance that is naturally present in the deeper layers of the skin, but declines as you age. Hyaluronic acid helps the skin retain water, and keeps it smooth and plump.

HA fillers are therefore able to soften and hydrate the skin, add volume, and diminish fine lines and wrinkles. They are often preferred for facial rejuvenation, because they can be reversed if desired.

The Restylane family of products which includes Defyne, Refyne, Silk, and Lyft, are all derived from HA. They reshape the face for a more youthful look, but target different areas of the face.


Restylane® Defyne

Restylane Defyne is a HA filler that is specially formulated to smooth moderate-to- severe deep expression lines, known as nasolabial folds and marionette lines.

Nasolabial folds (smile lines) run down from either side of the nose to the corner of the mouth, while marionette lines are the creases that can be seen alongside the mouth and often run down to the chin.


Restylane® Refyne

Restylane Refyne

Restylane Refyne is also FDA approved for the treatment of nasolabial folds. Refyne is a subtle formulation of HA that is ideal for mild to moderate folds. However, Defyne is a less flexible formulation, and for that reason it provides the added support needed to treat severe wrinkles and folds.

Defyne and Refyne are both next generation HA fillers that are made using XpresHAn Technology.  XpresHAn Technology is a process that gives the fillers a smooth consistency, and produces results that look entirely natural. The fillers can be tailored to satisfy the specific needs of each patient.

Both Restylane Defyne and Refyne are flexible fillers, and this makes them more effective than some of the other options now available for reducing smile lines.  They are approved for use by patients 21 years of age and older.

Both Defyne and Refyne produce natural looking results that typically last for 12 months.


Restylane® Silk

Restylane Silk

The lips often lose volume and become thin as a result of aging, Restylane Silk is designed to augment the lips, making them appear fuller and more youthful. It can also be used to fill in the lip lines near the mouth, also known as ‘smoker’s lines.’

Restylane Silk is a clear liquid gel that is also comprised of HA. It is a smooth injectable that is formulated using a high concentration of cross-linked chains of HA. Restylane Silk is infused with lidocaine, a local anesthetic often used in dermatologic treatments, which helps reduce any pain or discomfort during treatment.

Restylane Silk is not animal-based, so pre-testing for allergies is not required. There is no downtime after treatment, but patients may notice some slight swelling and bruising after treatment.


Restylane® Lyft

Restylane Lyft

Restylane Lyft is FDA approved for treating volume loss in the midface, and also for reducing smile lines.  Lyft is a firm formulation which makes it ideal for adding volume to the cheek contours, and filling in the temples. It can also be used to smooth nasolabial folds.

Restylane Lyft is injected into the targeted area using a tiny needle, but there is minimal pain, since it is also formulated with lidocaine.

Restylane Lyft will volumize and define the cheeks to give the midface a natural looking lift. The results typically last between 10-18 months.


Are you ready to revitalize and refresh your appearance?

Contact Privet Aesthetics, Beverly Hills and Pasadena, to find out more. Call (310)-860-8915 for the Beverly Hills practice and (626)-537-3737 for the Pasadena location.

Leif Rogers, MD, FACS
Dr. Rogers is certified in the field of plastic and reconstructive surgery by the American Board of Plastic Surgery and is thoroughly trained in reconstructive techniques for much of the human body.
Leif Rogers, MD, FACS


A New Sophisticated Aesthetics Center by Dr. Leif Rogers 📍Beverly Hills and Pasadena 👄Cosmetics and Lasers ☎️(310)860-8915
Book online today for #CyberMonday learn about the latest in non surgical procedures to help fit your needs!… - 8 years ago
Leif Rogers, MD, FACS
Leif Rogers, MD, FACS

Leif Rogers, MD, FACS

Dr. Rogers is certified in the field of plastic and reconstructive surgery by the American Board of Plastic Surgery and is thoroughly trained in reconstructive techniques for much of the human body.

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