From Tampa International Airport
- Total Distance: 40.4 miles
- Estimated Time: 43 minutes
- Head northeast on George J Bean Pkwy toward Airport Access Rd – 1.7 mi
- Take the ramp to TAMPA – St PETE/FL-60/I-275 – 0.2 mi
- Keep right at the fork, follow signs for Veterans Expy/FL-589 and merge onto FL-589 N/FL-60 W. Continue to follow FL-589 N (Partial toll road ) – 27.9 mi
- Take exit 27 for FL-52 toward San Antonio/Dade City (Toll road) – 0.2 mi
- Keep left at the fork, follow signs for Port Richey (Toll road) – 0.1 mi
- Continue straight – 92 ft
- Slight left at FL-52/State Rd 52 – 381 ft
- Slight right to stay on FL-52/State Rd 52 – 3.2 mi
- Slight left to stay on FL-52/State Rd 52 – 4.1 mi
- Turn right at Little Rd – 0.6 mi
- Turn left at Fivay Rd – 2.3 mi
- Turn left at Hudson Ave
- Gulf Coast Beaches
- Tarpon Springs
- Weeki Wachee Springs State Park
- Busch Gardens
- Manatee Springs
- Florida Aquarium
- Sunken Gardens